Police have closed the road between Arreton and Downend this afternoon (Friday).
A number of police cars are on scene, near to the junction with the main road, following a crash.
Drivers are being diverted via Blackwater and Newport, or Merstone.
A police spokesperson told Isle of Wight Radio:
"We were called at 11.54am today (Friday) to a report of a two vehicle collision on Arreton Road involving a red Mazda and red Ford B-Max-Zetec. Minor injuries have been reported."
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