People are feared trapped following a crash on the main Godshill to Whitwell road.
Police are in attendance on Whitwell Road, Godshill.
The road is currently closed.
Two vehicles — a car and a van — are said to have been involved.
A car is on its side.
Drivers are urged to find an alternative route.
*Updated
*Two people have been taken to hospital following a crash near Godshill.