Part of Sandown Road in Lake will be closed for 12 hours - so the walkway for Skew Bridge can be reinstated.
Island Roads says the closure will be in place between the Sandown Road (Cemetery Road junction) from 7pm tonight (Monday) to 7am tomorrow (Tuesday).
Islanders will be diverted via Sandown Road, Newport Road, Whitecross Lane, Sandy Lane, Landguard Manor Road, Landgaurd Road, Marine Cross Road, Regent Street, Atherley Road, and Wilton Park Road.
Southern Vectis says routes two and three will also be diverted.