Hampshire and Isle of Wight Air Ambulance has completed its 4000th mission.
The landmark call-out was to the Isle of Wight, where a patient needed to be conveyed to Southampton General Hospital.
John Perry, chief Executive of Hampshire and Isle of Wight Air Ambulance, said: "We are enormously pleased to announce this milestone in the life of this vital charity.
"With doctors flying more frequently on board, the air ambulance can bring enhanced pre-hospital skills directly to the patient at the scene, and the ability to take a seriously ill patient to the most appropriate hospital for their needs, sometimes after dark, can have a dramatic effect on the outcome for the patient.
"Hampshire and Isle of Wight Air Ambulance receives no government or national lottery funding for operational purposes, and relies solely on the generosity of you, the people and businesses of Hampshire and the Isle of Wight.
"It is only with your support that we are able to bring this service to patients who desperately need it.
"This is a fantastic achievement for such a young charity, and all in our 5th birthday year."